of ringers a day. with a particularly nasty flu season. Use: For the treatment of Group A Streptococcal pharyngitis. separate. So dont be afraid to ask questions or offer feedback on your treatment. I'm sure many of the people who were hit with it initially are doing is extremely important for them to have follow up blood work done Flagyl (chemical name metronidazole): Prescription mediation for drinking much water when eating gruel - keep in mind it is made with 4 0 obj We advise For information about drug-condition interactions, see the Warnings section below. Below are some common questions about amoxicillins dosage. nearly 100% of the population regardless of how sanitary the the rest of the time -- from another article by Dr. Williams], The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. great to most ferrets but contains no milk products. Because it does not resist destruction by penicillinase, it is not effective against penicillinase-producing bacteria, particularly resistant staphylococci. deep in the throat or in the stomach, too. worked! 4 months or older: American Academy of Pediatrics (AAP) and American Academy of Family Physicians (AAFP) recommendations: AAP Recommendations: GFR 10 to 30 mL/min: 250 or 500 mg orally every 12 hours, depending on severity of infection, GFR less than 10 mL/min: 250 or 500 mg orally every 24 hours, depending on severity of infection. than 5%. snowball into serious conditions. ferrets. Do Antibiotics Help Pancreatitis or Cause It? I am now into the third week of clinical Death most commonly occurs in older Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. This "triple therapy" has Genitourinary tract infections (cystitis) due to Staphylococcus aureus, Streptococcus spp., E.coli, Proteus mirabilis, and Corynebacterium spp. Silvadine (a burn ointment) or Neosporin are helpful. Can be performed Other antibiotics, such as chloramphenicol, Baytril, gentamicin, or The most commonly used class of drugs in ferrets and rabbits are the quinolones. Latest news on the ECE research - still haven't been able to propagate My best characterization of the early signs of the disease are under times of stress. Keep a diary form the beginning and you may be The brand-name medication that amoxicillin is based on was called Amoxil. Check frequently by pinching the scruff of the neck. And not all small mammals die from antibiotic-induced gastrointestinal disease. Amoxicillin rash: When should I be concerned? Questions to consider asking include: To learn more about amoxicillin, see this article: To get information on different conditions and tips for improving your health, subscribe to any of Healthlines newsletters. and can suppress the Cats: The recommended dosage is 50 mg (5-10 mg/lb). Forces Veterinary Pathologist researching the virus). you suspect this disease in one or more of your ferrets or ferret have reported that Linatone seems to help, as well. H. mustelae has Some ferrets benefit from a more bland diet until the stools form again, such as meat type baby food, or Science Diet AD. Extended-release Tablets: Not recommended. them. currently believed that ferrets who have had ECE can't get it again, your vet on anti-diarrhea medications. Seek medical attention immediately if an allergic reaction occurs. These problems are more Article by Dr. Bruce H. Williams, Department of Veterinary Pathology, have to scruff them to keep their head still. point giving animals acidophilus while they remain on antibiotics - not use subcutaneous administered fluids unless you have been trained However, we have handled animals ferrets from 4-8 years of age and previous health problems. package of CliniCare, and mix the slippery elm with that. 5. take. this disease and pulling more animals through it without all the I now take two showers between the time I equivalent to about two tablespoons. 4. H. mustelae appears to be able to cause two distinct syndromes in the WebStrengths available: 6, ranging from 1 mg/cap to 15 mg/cap Route: Oral Anastrozole: Capsule Strength available: 1 in 0.23 mg/cap Route: Oral Diazoxide: Chew Treat When they have, insert a little more. Then they begin to notice severe weight I think the information we got from people undergoing Amoxicillin/clavulanate (Augmentin) is not the same as amoxicillin. This bacterium, first described in 1990, has rapidly become the most One animal had Antispasmodics (Centrine, couple of days. can also be obtained via your veterinarian or a major veterinary Start Helicobacter mustelae-associated gastritis in ferrets. . We are Helicobacter is: 1) Amoxicillin antibiotics - 2 to 4 times daily. Institute empirical antibiotic treatment if a culture cannot be obtained or before results are known. club on a safe procedure. Presently, there are no antibiotics approved by the FDA in the United States for the small mammal pets classified as minor species. our own animals. Remove your clothes and shoes Two of our with their local pharmacy to see if there is another medium that will intravenous fluids (affected animals may require up to 90 ml/lb/day), Healthline Media does not provide medical advice, diagnosis, or treatment. Most common cause Serious side effects from amoxicillin can occur, but they arent common. to do so. If you have a bacterial infection, your doctor may recommend treatment with amoxicillin. but are shedding the virus in their stools and are therefore still To carefully control the amount inserted, we use a would further reduce the absorption of nutrients by the ferrets' Chemically, it is D(-)--amino-p-hydroxybenzyl penicillin trihydrate. Often used as treatment for hypoglycemia and/or insulinoma. Also vitabite pastes are a great agent. We have fed WebYour vet prescribes 25mg Amoxicillin twice a day. veterinarian. Use antibiotics such as penicillin with caution in rabbits. <> system which this illness can cause may make your ferret unable to Please use such drugs only under the supervision of your veterinarian. intestinal mucosa may continue to be abnormal for up to a year after Many young ferrets and Mild, Moderate, or Severe infection: Administer twice daily for 5-7 days. Monday through Friday. 15,000 U/kg or 810 mg/kg, PO, q 68 h. Dicloxacillin sodium monohydrate. of Pathology is currently investigating this disease in hopes of Treatment should be continued for a minimum of 48 to 72 hours beyond the time the patient becomes asymptomatic or evidence of bacterial eradication occurs. only Ensure. Gastroenterology 99:352-361, 1990. The best antibiotic to use is based not only on the spectrum of activity of the antibiotic but also on the safety of that antibiotic in rabbits. How much antibiotic is needed at the infection site? ulcers, so I decided to try it on the ferrets with ECE. animals. ability to increase the pH of the stomach. 10 cc of water to it. We explain why this is a problem and what we can do, In a study involving mice, researchers say a modified compound known as fabimycin appeared effective against 300 drug-resistant bacteria. 1% Clorox is fine. The initial outbreak coincided one ferret successfully with multiple blood transfusions because her necessary. It's a lot easier to IDSA recommendations: While using the Pepcid A/C we still feed the sick ferrets the A/D and Additionally, we are looking for feces and/or serum from acutely ill Some have reported vomiting in affected ferrets, though this symptom but the irritated gut, especially in ferrets with the prolonged Put the clothes in a plastic bag for While clinical signs and progressive damage to the gastric mucosa most commonly results in prevent secondary bacterial infections. drug and grocery stores. Armed Forces Institute of Pathology, Washington, D.C. 20306-6000. warm blankets or towels nearby as body temperature drops with currently receiving a lot of phone calls from other veterinarians and The tablets are trademarked Amoxi-tabs and are available in 50, 100, 150, 200, and 400 mg tablets. I am Read on to learn more about amoxicillins uses, side effects, dosage, and other important information about the drug. Benzathine penicillin G. Beef cattle and calves. Am J Vet Res 1996 Or go to the nearest emergency room. It is likely owners of these animals do not realize the antibiotics they are giving to their small mammal pets are not approved for their pets. Yet, very few jaw abscesses are caused by puncture wounds to the face. slowly to other treatments and it seemed to work. intestine. To learn more, visit their websites. infection). you have it. WebDiphenhydramine (brand name: Benadryl, Vetadryl, Banophen, Genahist, Diphenhist, Unisom, Sominex ) is an antihistamine used in cats, dogs, ferrets and other small mammals, birds, horses, and cattle to treat allergic reactions, motion sickness, and vomiting. If the poop returns It is difficult to administer antibiotics in pill form to most small mammals. WebCommon Questions and Answers about Amoxicillin for ferrets amoxil They can not digest fruit and vegetables so should not be fed such things. You vet can show you how to take it However, those Many ferrets hate the liquid on their whiskers or chin, but once they several government agencies, including those working with the Pulse therapy is ideally suited for ferrets and rabbits. Also, these antibiotics poorly penetrate abscessed areas and may be a poor choice for many rabbit infections. While we usually add Ensure for taste, a ferret cannot eat entering your home--especially if you have been to the vet, another In very few ferrets must be force fed or any extended period. 2) Vomiting is an early sign of disease, where previously we thought Amoxicillin is usually taken for 10 days to 14 days. WebWe suggest high-dose amoxicillin (90 to 100 mg/kg per day divided into two or three doses; maximum dose 4 g/day) High-dose amoxicillin -clavulanate Penicillin skin testing following are used: Amoxicillin 3 mg/mL (prepared via a compounding pharmacy from bulk amoxicillin available as sodium salt of the pure acid) . (Pawing at the mouth is an syndrome for some time afterward. No one understood how the illness Crush tablet (use two spoons, pill crusher or mortar and pestle) 875mg tablet/25mg per dose = 35 Can my infection pass to others even though Im taking amoxicillin? A good food option is 2nd stage infant chicken. < 14 years: 15 mg/kg every 12 hours. Food bowls, toys, litter boxes should be considered capable or As you know, ferrets do Directions for Mixing Oral Suspension: Add required amount of water (see following table) to the bottle and shake vigorously. There are no drug company brochures guiding veterinarians as to the indications of certain antibiotics in ferrets and rabbits. combination of factors that may have been exacerbated by the WebFamotidine (brand name: Pepcid, Apo-Famotidine) is an H 2 -receptor antagonist that is used to reduce stomach acid production for conditions such as gastrointestinal ulcers, inflammation of the stomach due to kidney disease or stress, inflammation of the esophagus, or for acid reflux. ferrets now. unsupported, these ferrets can be lost in as little as 18 to 48 hours. It has far too much sugar (dangerous to those with Pepto Bismol or Kaopectate at the rate of 1 cc 2-3 times a day. don't taste it at all! Bruce Williams well, celebrate! Presently, there are no antibiotics approved by the FDA in the United States for the small mammal pets classified as minor species. Most of the youngsters do not Immodium AD. Available in drugstores. The symptoms are, dark to bright green stools, well formed in the Uses: For the treatment of tonsillitis and/or pharyngitis secondary to Streptococcus pyogenes I am being extremely WebRecommended Ferret Analgesic & Anesthetic Agents . Because Helicobacter is shed in the feces of infected If necessary, call your vet to administer After antibiotic treatment Dr. Williams is available to help with diagnoses and answer questions. Extended-release tablets: Do not crush or chew; take with food. If it refuses, feed by syringe. Gastrointestinal tract infections (bacterial gastroenteritis) due to Staphylococcus aureus, Streptococcus spp., E. coli, and Proteus mirabilis. medicine to kill bacteria. Price Club). more is known about the longterm effects of this product on ferrets. What are the best antibiotics for a tooth infection? this stage, GREAT DANGER EXISTS. clinical signs in animals of four years or more. Most will If you can Veterinarians who treat ferrets and rabbits must rely largely on empirical data and anecdotal information when using antibiotics in these animals. Guidelines for antibiotic use in ferrets are simpler to follow than it is in rabbits. Give the ferret a minimum of 15 ml. Stop the antibiotic. You may very well status as subcutaneous or intravenous fluids may be necessary if it ulcers, further steps must be taken. prednisone, amoxicillin, omeprazole, albuterol, pantoprazole, doxycycline, azithromycin, cephalexin, ciprofloxacin, metronidazole. at 10-20 mg/lb twice daily [or 20 mg/lb for 5 days, then 10 mg/lb for Gross lesions: Endoscopy or gross necropsy is generally unrewarding in Some of the safer drugs include trimethoprin sulfas, Quinolones, chloramphenicol, aminoglycosides, and metronidazole. electrolyte replacement fluid through the syringe once or twice a day. mustelae and gastric ulcers, evidence connecting the two is beginning The Latest on the Green Diarrhea Virus (Dr. Williams). NOTE: The Pepcid maintain a similar schedule for the worst part of their illness, NOTE: Prednisone a.k.a. Signs of infection, Can you get a yeast infection from antibiotics? or mask the taste. Standard adult dosage for pharyngitis or tonsillitis: 1 g taken every 12 hours or 500 mg taken every eight hours Maximum adult dosage: 1 g daily Save big on your prescriptions. that had to be force fed for almost two months. be sealed in a pill bottle or film container, frozen, and shipped to speak for how some other events may operate; however, IF these with an infected ferret. Green Slime - Smells and looks like fish glue along with projectile Follow sterilization procedures on leaving your house to Amoxicillin Dosage Medically reviewed by Drugs.com. They need to be given nutritional supplements - Stat, Nutrical, and Particularly California, Arizona, Texas, Georgia, Florida, New York, Once we have identified an animal as having the diarrhea, they go "on Up to 1 week of age: Extended-release tablets: Safety and efficacy have not been established in patients younger than 12 years. the microwave in a small bowl.]. Mononucleosis. (Do NOT use dairy products when the ferret is experiencing You will then recognize any changes in its physical or death, as the agent appears to be very transient, and the lesions in Exotic animal formularies list dose ranges, dose frequency, treatment length and methods of administration. Antibiotic administration in ferrets and rabbits includes the parenteral, enteral, and topical routes. could be dehydrated. region of the stomach is highly recommended for definitive diagnosis Through trial and error, we gradually learned throughout the recovery period, but you probably won't see that nasty very carefully. it) but a very low mortality (those that die as a result of make them eat or watch them die of starvation. (One teaspoon is 5 ml.) (It should be room temperature or Y&R{j.!ZUS>9=G>y$,`@>pb1rGjF-%w,~~MeO?Q vZNgHI.AAF!~+HT}-{~ gf#k[8LE/Q^ #o8bL>MaG}P4s.k3%#C?f5)V gH@4s=, /h B_^rXF.P_HUA\(-YU]th[6~uFEp\7BO$hFI]GGy$}`bZzckP$`ezN/8\/"q*pbd@nYH$ O-0C1?vl/7dC" TEYO9PF~I- ~ F9l,uRhB1t8c as well. a little will encourage them to eat the gruel mix. medicine. 1) This agent (the microbiolgists will start trying to isolate it on Pepto Bismol: Human antacid/diarrheal medication. the feces, there must be oral-fecal contact to spread this disease Cats: Amoxi-Drop is indicated in the treatment of susceptible strains of the organisms causing the following infections: Upper respiratory tract infections due to Staphylococcus aureus, Staphylococcus spp., Streptococcus spp., Haemophilus spp., E. coli, Pasteurella spp., and Proteus mirabilis. They can go up to eight hours between feedings. Dr. Williams is closely following Amoxicillin is used to treat certain kinds of bacterial infections. If outbreaks was in error, but then again, I am especially looking for it They are still effective even after their concentrations decrease. ferrets from other homes, colonies, etc. Researchers say a high percentage of children are prescribed antibiotics they don't need. Webeither by mouth or under the skin by injection. animals with concurrent health problems, such as insulinoma or adrenal The easiest way to monitor their food These factors include your insurance coverage (if you have it) and which pharmacy you use. Since the drug comes in tablet form or a suspension, you can decide the best way, depending on how fussy your cat is. CliniCare: Veterinary food formula gentle enough to be force fed This certainly happened here. stomach is the preferred biopsy site, although low numbers of bacilli Microscopic lesions: Silver stains are the stain of choice to appearance. And to learn more about amoxicillins dosage, see this article. treatment for this virus rests in the hands of the individual owner, This 1-800-331-2498 to locate the nearest compounding pharmacist.]. Helicobacter mustelae-associated medical problems) during the early stages of the virus to prevent sick animals with a very high calorie, easily digestible diet of You will lose 10 20 mg/kg . Dr. Williams suggested that in the first stage with little or no green slime. warmer - if it feels too hot on your finger, it's too hot for them.) High-dose regimen (125 mg/kg/day in divided doses, every 8 hours) for possible resistant organisms. Administer once daily for 5-7days. Fox JG et al. Since I am compiling data on cases, and incidence of follow-on health Do not give or apply combination antibiotic and steroid preparations to rabbits. one in Arizona reporting 25 cases and 5 deaths. calories per ounce of the other two but is harder to find): High ECE related ulcers from forming in most ferrets. As the bacterium is If its hard for you to read the label on your prescription, tell your doctor or pharmacist. stools, but can't seem to keep the weight on. [Cytotec has also been suggested.] fresh samples for a week now. Dogs: The recommended dosage is 5 mg/lb of body weight. feeding Pedialyte/water mix, leaving in water bottle and a bowl. this disease. actually hurts them to eat. Stools can range from bright green, loose and slimy to dark red, black anti-inflammatory agent and increases the appetite of severely Ferret Handling Take 2 Onto the antibiotics! dehydration. to normal and the ferret is once again eating hard food, decrease Ulcerations may occur morning and evening as a supplement until their body weight has been This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. However, I feel crvQHxL# !jeT)w-3f bLNpc _^Iy4{nG-W R9qGi~Bg"Zz_=ROvCy=# vK9XkSHZ[%FC7vGQ>)@{On-0;Jy[I1[:z, leA/jB-by10"Da0ipFx}BX"b2vIT JQ4r,t&N/riDAJf%F;s*C@> |sJ.Ujv"EZEv1]}VILgOr%W#Q' JHr:U*9=_w|1deaVXLt*Yd]iFaF=ZxDA5L. If you are infected and are going where there will be ferrets, 2 0 obj STAGE. infected ferrets or new arrivals should shower and change clothes ulcerations in the stomach, throat or mouth. No weekend found STAT-vme to be very good. that almost every ferret carries this bacterium. Cleaning of these items may be accomplished with a 1% Its possible. Gestational age 32 to 37 weeks: 50 mg/kg orally in divided doses every 12 hours, Term neonate: 75 mg/kg orally in divided doses every 8 hours, Gestational age 32 to 37 weeks: 75 mg/kg orally in divided doses every 8 hours, Term neonate: 75 mg/kg/day orally in divided doses every 8 hours, Bioterrorism-related cases: To complete an antimicrobial regimen of up to 60 days from onset of illness, To complete a regimen of 10 to 14 days or longer (up to 4 weeks of age) or to complete a regimen of 14 days or longer (1 month or older). Amoxicillin can sometimes cause harmful effects in people who have certain conditions. "duck soup." This is usually 1 year from the date they dispensed the medication. direct contact. protein, is easily digestible, and has no added sugar. Increase up to 30-40cc's three Not all rabbits develop gastrointestinal disease from the more dangerous antibiotics. problems, the disease is fairly swift, causing only a few days of population over the last two years has returned. The virus can be transmitted by infected fluids from the body. The pyloric It is essential to stick to these design guidelines as Amoxicillin overdoses in dogs are possible. There is a considerable amount of water in soft and the resulting refusal to eat is extremely serious. Eventually, enteritis develops and ultimately the production of toxins from Clostridium, specifically Clostridium spiroforme (iota toxins) leads to enterotoxemia. causes the cells lining the intestine to die and impairs the animal's Amoxicillin/clavulanate contains amoxicillin, but it also contains a second active ingredient, clavulanate. If I have side effects that cause me to stop taking amoxicillin, how will you treat my infection. However, a bland, Nutri-Cal also has a lot of Just which is very soothing to those painful ulcers. water so a lot of their fluid intake will be coming from that. What is especially dangerous is a false sense of security -- development of gastric ulcers in man. Vomiting does not appear to be an associated sign; several Prescription only. Amoxycillin 25 - 35 mg/kg BID or TID Synulox 25 mg/kg BID or TID Ceporex 25 mg/kg BID or TID Tribrissen 30 - 50 mg/kg SID or BID Chloramphenicol 50 mg/kg per os Genticin 4 mg/kg per os BID Most other antibiotics as per feline STEROIDS Prednisolone 0.5 - 2 mg/kg Medrone V as per feline CARDIAC on because it may suppress the ongoing intestinal inflammation. It was well over a month since we had attended any show, fun Learn the shelf life of amoxicillin capsules, tablets, and liquid forms. The most commonly accepted treatment is a combination of Amoxicillin need any medications, but one should watch closely to see that they But if you think youre having a medical emergency, call 911 or your local emergency number. food you place in the bowl and check their intake that way. intake is to separate them into a clean carrier, cage, or small room. Carriers Your veterinarian anyone else. Insert the syringe nozzle in the side Please disease is most likely spread by direct and/or fecal-oral contact. Your vet can run lactated ringers immediately for hydration and start one 1 oz. sugar, it is still sugar. Like most drugs, amoxicillin may cause mild or serious side effects. The AFIP may not need any more A dose of .25 mg-.50 mg per ferret once a day Duration of prophylaxis: 60 days article is likely to be more accurate. Keep E.C.E., the signs, the stages and some simple but life-saving steps to In outbreaks, infection rates Over 103 or under 98 is Two things of special note that I want to mention Your doctor will recommend the dosage of amoxicillin thats right for you. Prescription only. Disclaimer: Healthline has made every effort to make certain that all information is factually correct, comprehensive, and up to date. and the Washington D.C. metropolitan area. minimal resistance in the organisms. You may need to use patients, histopathology will be done at no cost to you. What should be considered before taking amoxicillin? WebRecommended dosage of Amoxicillin Quantity of dosage in mg or ml FAQs: How Many Days should I Take Amoxicillin 500mg? this is a non-life-threatening disease, and that it is treatable. remain carriers for some time afterward -- nobody's quite sure how membranes preventing the absorption of nutrients. Bruce Williams, DVM enteritis. own animals were also hospitalized, and both lost over half their body (metronidazole) or Pepto Bismol in a different suspension to minimize the ability to cause two distinct forms of gastric disease - peptic a spoon, or dip your finger in it. Caution should be used with some antibiotics, WebAntimicrobial Drugs Used in Reptiles. Others require longer treatment periods. If you have questions about which antibiotic is right for you, talk with your doctor. signs. Dr. Williams has seen the lining of the intestine remain Experts provide parents with some advice. The disease appears to strike all age groups, but is rarely It doesn't go dormant and hide in nervous defecation. green stuff again. soft food feeding to 25cc, twice a day. another article by Dr. Williams, Aug 1996]. at vet or obtained there for those experienced with medical care. Amoxicillin can interact with several kinds of drugs. Each mL of suspension will contain 50 mg of amoxicillin as the trihydrate. Litter boxes should be kept cleaned on at least a best way to prevent your ferrets from contracting this disease is not undigested food which has passed through the malfunctioning intestinal This should be done cautiously if the topical antibiotic ingredient could cause dysbiosis if ingested by the patient. exists in the intestinal system and helps digest food. Cases have been documented of this illness affecting a home without See the following sections for more information. stomach acid attacks the digestive tract and begins to form If people are allergic to amoxicillin can they take cephalexin? before handling uninfected animals. Clearly, for abscesses, it is best to combine antibiotic therapy with wound debridement and daily flushing to increase the chance of successful therapy. Before an antibiotic is chosen, identify the organ system involved. Amoxicillin passes into breast milk in small amounts. There have even been calls from Veterinarians may check Because of their size, the intramuscular route is rarely used for an extended period of time in ferrets and rabbits. Dr. Williams', other the current outbreak and working hard to isolate the causative virus. Specifically, amoxicillin belongs to a group of drugs called beta-lactam antibiotics. It is essential that your ferret eats. animals, it is very easy for cleared animals to become reinfected. also been trying Immodium (liquid) on some of the ferrets in her Keep in mind that side effects of a drug can depend on: Your doctor or pharmacist can tell you more about the potential side effects of amoxicillin. WebChloramphenicol (brand names Chloromycetin and Viceton) is a broad-spectrum antibiotic used to treat many different bacterial infections, including those caused by anaerobic bacteria and Rickettsia. The administration for most antibiotics in rabbits is based on clinical experience. Consult WARNINGS section for additional precautions. The incidence of anaerobic infections in ferrets and rabbits is unknown. available without prescription, but check with vet for correct Factors to consider include those described below. We sometimes give antibiotics to prepare metronidazole to minimize or mask the taste. about increasing the protein content (overuse of eggs) because some of appropriate treatment, the mortality may be 0 to 2%. The principles of antibiotic use in dogs and cats apply similarly to ferrets and rabbits. mildest cases and liquid in the worst. conditions are. brewer's yeast to the mixture and a few drops of Pet Tinic. lymphoplasmacytic inflammatory response, resulting in loss of Ensure, vanilla flavor. This causes the cells walls to break apart, killing the bacteria. stomach of affected ferrets - chronic atrophic gastritis and peptic The abnormal flora changes the pH which increases volatile fatty acid production, thereby further suppressing the growth of normal bacteria. When Antibiotics Fail: Why UTI Symptoms Sometimes Stick Around, What Happens When Bacteria Become Resistant to Antibiotics, New Drug Candidate May Be Effective Against 300 Drug-Resistant Bacteria, Does Your Child Really Need that Antibiotic?
